Endocrine Abstracts

Background: Many drugs are known to cause thyroid dysfunction. We describe a patient with hypothyroidism due to isotretinoin.Case: A 28 year-old Chinese gentleman presented with 2-year history of fatigue and cold intolerance. He has acne vulgaris and has been taking isotretinoin for the last 3 years (20 mg daily for 1 year then 10 mg daily). He has a positive family history of thyroid disorders. He did not report any history of thyroiditis or known autoi...